High-Mobility Group Box-1 Protein Promotes Angiogenesis After Peripheral Ischemia in Diabetic Mice Through a VEGF-Dependent Mechanism

OBJECTIVE: High-mobility group box-1 (HMGB1) protein is a nuclear DNA-binding protein released from necrotic cells, inducing inflammatory responses and promoting tissue repair and angiogenesis. Diabetic human and mouse tissues contain lower levels of HMGB1 than their normoglycemic counterparts. Defi...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Biscetti, Federico, Straface, Giuseppe, De Cristofaro, Raimondo, Lancellotti, Stefano, Rizzo, Paola, Arena, Vincenzo, Stigliano, Egidio, Pecorini, Giovanni, Egashira, Kensuke, De Angelis, Giulia, Ghirlanda, Giovanni, Flex, Andrea
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2010
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874711/
https://ncbi.nlm.nih.gov/pubmed/20200317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1507
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk