Prevention of Diabetes by FTY720-Mediated Stabilization of Peri-Islet Tertiary Lymphoid Organs

OBJECTIVE: The nonobese diabetic (NOD) mouse is a well-established mouse model of spontaneous type 1 diabetes, which is characterized by an autoimmune destruction of the insulin-secreting pancreatic β-cells. In this study, we address the role of tertiary lymphoid organs (TLOs) that form in the pancr...

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Detaylı Bibliyografya
Asıl Yazarlar: Penaranda, Cristina, Tang, Qizhi, Ruddle, Nancy H., Bluestone, Jeffrey A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2010
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874707/
https://ncbi.nlm.nih.gov/pubmed/20299465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1129
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