Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplasmic Reticulum Stress In Vivo

OBJECTIVE: The oxidation of LDLs is considered a key step in the development of atherosclerosis. How LDL oxidation contributes to atherosclerosis remains poorly defined. Here we report that oxidized and glycated LDL (HOG-LDL) causes aberrant endoplasmic reticulum (ER) stress and that the AMP-activat...

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Detalhes bibliográficos
Main Authors: Dong, Yunzhou, Zhang, Miao, Wang, Shuangxi, Liang, Bin, Zhao, Zhengxing, Liu, Chao, Wu, Mingyuan, Choi, Hyoung Chul, Lyons, Timothy J., Zou, Ming-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874699/
https://ncbi.nlm.nih.gov/pubmed/20299472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1637
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