Effect of Endogenous GLP-1 on Insulin Secretion in Type 2 Diabetes

OBJECTIVE: The incretins glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) account for up to 60% of postprandial insulin release in healthy people. Previous studies showed a reduced incretin effect in patients with type 2 diabetes but a robust response to exogeno...

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Bibliografiske detaljer
Main Authors: Salehi, Marzieh, Aulinger, Benedict, Prigeon, Ronald L., D'Alessio, David A.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2010
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874693/
https://ncbi.nlm.nih.gov/pubmed/20215429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1253
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