The TNF-Like Protein 1A–Death Receptor 3 Pathway Promotes Macrophage Foam Cell Formation In Vitro

TNF-like protein 1A (TL1A), a TNF superfamily cytokine that binds to death receptor 3 (DR3), is highly expressed in macrophage foam cell-rich regions of atherosclerotic plaques, although its role in foam cell formation has yet to be elucidated. We investigated whether TL1A can directly stimulate mac...

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Detalhes bibliográficos
Main Authors: McLaren, James E., Calder, Claudia J., McSharry, Brian P., Sexton, Keith, Salter, Rebecca C., Singh, Nishi N., Wilkinson, Gavin W. G., Wang, Eddie C. Y., Ramji, Dipak P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874519/
https://ncbi.nlm.nih.gov/pubmed/20410491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903782
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