A miniature mimic of host defense peptides with systemic antibacterial efficacy

Oligomers of acylated lysines (OAKs) are synthetic mimics of host defense peptides (HDPs) with promising antimicrobial properties. Here we challenged the OAK concept for its ability to generate both systemically efficient and economically viable lead compounds for fighting multidrug-resistant bacter...

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Main Authors: Sarig, Hadar, Livne, Liran, Held-Kuznetsov, Victoria, Zaknoon, Fadia, Ivankin, Andrey, Gidalevitz, David, Mor, Amram
Formato: Artigo
Idioma:Inglês
Publicado: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Research Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874476/
https://ncbi.nlm.nih.gov/pubmed/20124435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-149427
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