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A miniature mimic of host defense peptides with systemic antibacterial efficacy

Oligomers of acylated lysines (OAKs) are synthetic mimics of host defense peptides (HDPs) with promising antimicrobial properties. Here we challenged the OAK concept for its ability to generate both systemically efficient and economically viable lead compounds for fighting multidrug-resistant bacter...

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Hlavní autoři: Sarig, Hadar, Livne, Liran, Held-Kuznetsov, Victoria, Zaknoon, Fadia, Ivankin, Andrey, Gidalevitz, David, Mor, Amram
Médium: Artigo
Jazyk:Inglês
Vydáno: The Federation of American Societies for Experimental Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874476/
https://ncbi.nlm.nih.gov/pubmed/20124435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-149427
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