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An Epigenetic Hypothesis of Aging-Related Cognitive Dysfunction

This brief review will focus on a new hypothesis for the role of epigenetic mechanisms in aging-related disruptions of synaptic plasticity and memory. Epigenetics refers to a set of potentially self-perpetuating, covalent modifications of DNA and post-translational modifications of nuclear proteins...

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Detalhes bibliográficos
Main Authors: Penner, Marsha R., Roth, Tania L., Barnes, Carol A., Sweatt, J. David
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874394/
https://ncbi.nlm.nih.gov/pubmed/20552047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2010.00009
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