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Intercellular adhesion molecule 1 is induced on isolated endocrine islet cells by cytokines but not by reovirus infection.

The selective destruction of the pancreatic islet beta cells in type 1 diabetes mellitus is thought to be mediated by a cellular autoimmune process, possibly triggered by virus infection in genetically susceptible individuals. Because of the potentially important role of cell-cell adhesion in the im...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Campbell, I L, Cutri, A, Wilkinson, D, Boyd, A W, Harrison, L C
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2498883/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.11.4282
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