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siRNA Delivery to CNS Cells using a Membrane Translocation Peptide
[Image: see text] We report the generation and characterization of a peptide-based siRNA probe for ischemic stroke treatment. Complexing siRNA with myristoylated polyarginine peptides promoted probe uptake by primary and transformed cells and protection from serum nucleases. Application of siRNA pro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874326/ https://ncbi.nlm.nih.gov/pubmed/20420373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900488e |
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