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siRNA Delivery to CNS Cells using a Membrane Translocation Peptide

[Image: see text] We report the generation and characterization of a peptide-based siRNA probe for ischemic stroke treatment. Complexing siRNA with myristoylated polyarginine peptides promoted probe uptake by primary and transformed cells and protection from serum nucleases. Application of siRNA pro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ifediba, Marytheresa A., Medarova, Zdravka, Ng, Shu-wing, Yang, Junzheng, Moore, Anna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874326/
https://ncbi.nlm.nih.gov/pubmed/20420373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900488e
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