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Evidence that the familial adenomatous polyposis gene is involved in a subset of colon cancers with a complementable defect in c-myc regulation.

Human colorectal carcinomas frequently express elevated levels of c-myc mRNA in the absence of a gross genetic change at the c-myc locus. To test the hypothesis that these tumors are defective in a gene function necessary for the regulation of c-myc expression, we fused an osteosarcoma cell line tha...

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Библиографические подробности
Главные авторы: Erisman, M D, Scott, J K, Astrin, S M
Формат: Artigo
Язык:Inglês
Опубликовано: 1989
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC287431/
https://ncbi.nlm.nih.gov/pubmed/2542967
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