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Pd(0)/PR(3)–Catalyzed Arylation of Nicotinic and Isonicotinic Acid Derivatives

[Image: see text] The first example of C-H functionalizations of pyridine rings at the 3- and 4-positions is developed using Pd(0)/PR(3)/ArBr. This reaction provides a powerful method for the preparation of structurally diverse nicotinic and isonicotinic acids that are of tremendous importance in dr...

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Detalhes bibliográficos
Main Authors: Wasa, Masayuki, Worrell, Brady T., Yu, Jin–Quan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874250/
https://ncbi.nlm.nih.gov/pubmed/20082399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.200906104
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