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Gliosarcoma stem cells undergo glial and mesenchymal differentiation in vivo

Cancer stem cells (CSCs) are characterized by their self-renewing potential, and by their ability to differentiate and phenocopy the original tumor in orthotopic xenografts. Long term propagation of glioblastoma (GBM) cells in serum containing medium results in loss of the CSCs and outgrowth of cell...

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Bibliographic Details
Main Authors: deCarvalho, Ana C., Nelson, Kevin, Lemke, Nancy, Lehman, Norman L., Arbab, Ali S., Kalkanis, Steven, Mikkelsen, Tom
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873790/
https://ncbi.nlm.nih.gov/pubmed/19937755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.264
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