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Computational predictions of the mutant behavior of AraC

An algorithm implemented in Rosetta correctly predicts the folding capabilities of the 17 residue N-terminal arm of the AraC gene regulatory protein when arabinose is bound to the protein and the dramatically different structure of this arm when arabinose is absent. The transcriptional activity of 4...

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Main Authors: Berrondo, Monica, Gray, Jeffrey J., Schleif, Robert
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873782/
https://ncbi.nlm.nih.gov/pubmed/20338183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.021
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