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Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma
Pigment epithelium-derived factor (PEDF) is a multifunctional secreted glycoprotein that displays broad anti-tumor activity based on dual targeting of the tumor microenvironment (anti-angiogenic action) and the tumor cells (direct anti-tumor action). Here we show that PEDF expression is high in mela...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873770/ https://ncbi.nlm.nih.gov/pubmed/19767774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.284 |
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