Initiation of simian virus 40 DNA replication in vitro: pulse-chase experiments identify the first labeled species as topologically unwound.

A distinct unwound form of DNA containing the simian virus 40 (SV40) origin is produced in replication reactions carried out in mixtures containing crude fractions prepared from HeLa cells. This species, termed form UR, comigrates on chloroquine-containing agarose gels with the upper part of the pre...

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Bibliographic Details
Main Authors: Bullock, P A, Seo, Y S, Hurwitz, J
Format: Artigo
Language:Inglês
Published: 1989
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC287364/
https://ncbi.nlm.nih.gov/pubmed/2542958
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