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Fine-scale detection of population-specific linkage disequilibrium using haplotype entropy in the human genome

BACKGROUND: The creation of a coherent genomic map of recent selection is one of the greatest challenges towards a better understanding of human evolution and the identification of functional genetic variants. Several methods have been proposed to detect linkage disequilibrium (LD), which is indicat...

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Autors principals: Mizuno, Hideaki, Atwal, Gurinder, Wang, Haijian, Levine, Arnold J, Vazquez, Alexei
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873552/
https://ncbi.nlm.nih.gov/pubmed/20416085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-27
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