A central nervous system defect in biosynthesis of corticotropin-releasing hormone is associated with susceptibility to streptococcal cell wall-induced arthritis in Lewis rats.

We have recently found that susceptibility to streptococcal cell wall (SCW)-induced arthritis in Lewis (LEW/N) rats is due, in part, to defective inflammatory and stress mediator-induced activation of the hypothalamic-pituitary-adrenal (HPA) axis. Conversely, the relative arthritis resistance of his...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Sternberg, E M, Young, W S, Bernardini, R, Calogero, A E, Chrousos, G P, Gold, P W, Wilder, R L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287355/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2786636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4771
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