The RNA binding protein HuR does not interact directly with HIV-1 reverse transcriptase and does not affect reverse transcription in vitro

BACKGROUND: Lemay et al recently reported that the RNA binding protein HuR directly interacts with the ribonuclease H (RNase H) domain of HIV-1 reverse transcriptase (RT) and influences the efficiency of viral reverse transcription (Lemay et al., 2008, Retrovirology 5:47). HuR is a member of the emb...

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Bibliografiske detaljer
Main Authors: Ahn, Jinwoo, Byeon, In-Ja L, Dharmasena, Sanjeewa, Huber, Kelly, Concel, Jason, Gronenborn, Angela M, Sluis-Cremer, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873509/
https://ncbi.nlm.nih.gov/pubmed/20459669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-40
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