Potent inhibition of tumoral hypoxia-inducible factor 1α by albendazole

BACKGROUND: Emerging reports suggest resistance, increased tumor invasiveness and metastasis arising from treatment with drugs targeting vascular endothelial growth factor (VEGF). It is believed that increased tumoral hypoxia plays a prominent role in the development of these phenomena. Inhibition o...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Pourgholami, Mohammad H, Cai, Zhao Y, Badar, Samina, Wangoo, Kiran, Poruchynsky, Marianne S, Morris, David L
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873385/
https://ncbi.nlm.nih.gov/pubmed/20398289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-143
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