Fowlpox virus recombinants expressing HPV-16 E6 and E7 oncogenes for the therapy of cervical carcinoma elicit humoral and cell-mediated responses in rabbits

BACKGROUND: Around half million new cases of cervical cancer arise each year, making the development of an effective therapeutic vaccine against HPV a high priority. As the E6 and E7 oncoproteins are expressed in all HPV-16 tumour cells, vaccines expressing these proteins might clear an already esta...

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Main Authors: Radaelli, Antonia, Pozzi, Eleana, Pacchioni, Sole, Zanotto, Carlo, Morghen, Carlo De Giuli
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873375/
https://ncbi.nlm.nih.gov/pubmed/20409340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-8-40
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