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The conformation change of Bcl-2 is involved in arsenic trioxide-induced apoptosis and inhibition of proliferation in SGC7901 human gastric cancer cells

BACKGROUND: Arsenic trioxide has been established as a first-line agent for treating acute promyelocytic leukemia. Experimental data suggest that arsenic trioxide also can have a potential use as chemotherapeutic agent for other malignancies. The precise mechanisms of action of arsenic trioxide have...

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Detalhes bibliográficos
Main Authors: Zheng, Yihu, Zhou, Mengtao, Ye, Aifang, Li, Qiu, Bai, Yongheng, Zhang, Qiyu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873337/
https://ncbi.nlm.nih.gov/pubmed/20403207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-8-31
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