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Mycobacterium tuberculosis senses host-derived carbon monoxide during macrophage infection

Mycobacterium tuberculosis (MTB) expresses a set of genes known as the dormancy regulon in vivo. These genes are expressed in vitro in response to nitric oxide (NO) or hypoxia, conditions used to model MTB persistance in latent infection. Although NO, a macrophage product that inhibits respiration,...

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Detalhes bibliográficos
Main Authors: Shiloh, Michael U., Manzanillo, Paolo, Cox, Jeffery S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873178/
https://ncbi.nlm.nih.gov/pubmed/18474359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2008.03.007
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