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Activation of NF-κB signaling by IKKβ increases aggressiveness of ovarian cancer

The NF-κB family of transcription factors has been implicated in the propagation of ovarian cancer, but the significance of constitutive NF-κB signaling in ovarian cancer is unknown. We hypothesized that constitutive NF-κB signaling defines a subset of ovarian cancer susceptible to therapeutic targe...

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Detalhes bibliográficos
Main Authors: Hernandez, Lídia, Hsu, Sarah, Davidson, Ben, Birrer, Michael J., Kohn, Elise C., Annunziata, Christina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873166/
https://ncbi.nlm.nih.gov/pubmed/20424119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3912
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