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Small molecules discovered in a pathway screen target the Rho pathway in cytokinesis
We report the discovery of small molecules that target the Rho pathway, a central regulator of cytokinesis, the final step in cell division. We have developed a method to target a small molecule screen towards a specific pathway, which should be widely applicable to study any signaling pathway. In a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873065/ https://ncbi.nlm.nih.gov/pubmed/20436488 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.363 |
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