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Metabolic oxidation regulates embryonic stem cell differentiation
Metabolites offer an important unexplored complement to understanding the pluripotency of stem cells. Using mass spectrometry-based metabolomics, we show that embryonic stem cells are characterized by abundant metabolites with highly unsaturated structures whose levels decrease upon differentiation....
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873061/ https://ncbi.nlm.nih.gov/pubmed/20436487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.364 |
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