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Piracetam Defines a New Binding Site for Allosteric Modulators of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors

Glutamate receptors are the most prevalent excitatory neurotransmitter receptors in the vertebrate central nervous system and are important potential drug targets for cognitive enhancement and the treatment of schizophrenia. Allosteric modulators of AMPA receptors promote dimerization by binding to...

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Detalhes bibliográficos
Main Authors: Ahmed, Ahmed H., Oswald, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872987/
https://ncbi.nlm.nih.gov/pubmed/20163115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm901905j
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