Escin, a Pentacyclic Triterpene, Chemosensitizes Human Tumor Cells through Inhibition of Nuclear Factor-κB Signaling Pathway

Agents that can enhance tumor cell apoptosis and inhibit invasion have potential for the treatment of cancer. Here, we report the identification of escin, a pentacyclic triterpenoid from horse chestnut that exhibits antitumor potential against leukemia and multiple myeloma. Whether examined by ester...

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Detalhes bibliográficos
Main Authors: Harikumar, Kuzhuvelil B., Sung, Bokyung, Pandey, Manoj K., Guha, Sushovan, Krishnan, Sunil, Aggarwal, Bharat B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872971/
https://ncbi.nlm.nih.gov/pubmed/20103608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.062760
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