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The Nonpsychoactive Cannabinoid Cannabidiol Inhibits 5-Hydroxytryptamine(3A) Receptor-Mediated Currents in Xenopus laevis Oocytes

The effect of the plant-derived nonpsychotropic cannabinoid, cannabidiol (CBD), on the function of hydroxytryptamine (5-HT)(3A) receptors expressed in Xenopus laevis oocytes was investigated using two-electrode voltage-clamp techniques. CBD reversibly inhibited 5-HT (1 μM)-evoked currents in a conce...

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Detalhes bibliográficos
Main Authors: Yang, Keun-Hang, Galadari, Sehamuddin, Isaev, Dmytro, Petroianu, Georg, Shippenberg, Toni S., Oz, Murat
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872948/
https://ncbi.nlm.nih.gov/pubmed/20160007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.162594
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