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Escherichia coli DNA helicase II (uvrD gene product) catalyzes the unwinding of DNA.RNA hybrids in vitro.

DNA helicase II is a well-characterized Escherichia coli enzyme capable of unwinding duplex DNA and known to be involved in both methyl-directed mismatch repair and excision repair of pyrimidine dimers. Here it is shown that this enzyme also catalyzes the ATP-dependent unwinding of a DNA.RNA hybrid...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Author: Matson, S W
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287283/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2543977/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4430
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