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Contrasting gray and white matter changes in preclinical Huntington disease: An MRI study

BACKGROUND: In Huntington disease (HD), substantial striatal atrophy precedes clinical motor symptoms. Accordingly, neuroprotection should prevent major cell loss before such symptoms arise. To evaluate neuroprotection, biomarkers such as MRI measures are needed. This requires first establishing the...

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Autors principals: Stoffers, D., Sheldon, S., Kuperman, J.M., Goldstein, J., Corey-Bloom, J., Aron, A.R.
Format: Artigo
Idioma:Inglês
Publicat: American Academy of Neurology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872799/
https://ncbi.nlm.nih.gov/pubmed/20385893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181d8c20a
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