Synaptic Clustering of PSD-95 Is Regulated by c-Abl through Tyrosine Phosphorylation

The c-Abl tyrosine kinase is present in mouse brain synapses, but its precise synaptic function is unknown. We found that c-Abl levels in the rat hippocampus increase postnatally, with expression peaking at the first postnatal week. In 14 d in vitro hippocampal neuron cultures, c-Abl localizes prima...

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Main Authors: de Arce, Karen Perez, Varela-Nallar, Lorena, Farias, Olivia, Cifuentes, Alejandra, Bull, Paulina, Couch, Brian A., Koleske, Anthony J., Inestrosa, Nibaldo C., Alvarez, Alejandra R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872795/
https://ncbi.nlm.nih.gov/pubmed/20220006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2024-09.2010
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