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In situ regulation of DC subsets and T cells mediates tumor regression in mice

Vaccines are largely ineffective for patients with established cancer, as advanced disease requires potent and sustained activation of CD8(+) cytotoxic T lymphocytes (CTL) to kill tumor cells and clear the disease. Recent studies have elucidated that subsets of dendritic cells (DCs) specialize in an...

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Detalhes bibliográficos
Main Authors: Ali, Omar A., Emerich, Dwaine, Dranoff, Glenn, Mooney, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872791/
https://ncbi.nlm.nih.gov/pubmed/20368186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000359
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