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Testing the effects of FSHD candidate gene expression in vertebrate muscle development

The genetic lesion leading to facioscapulohumeral muscular dystrophy (FSHD) is a dominant deletion at the 4q35 locus. The generally accepted disease model involves an epigenetic dysregulation in the region resulting in the upregulation of one or more proximal genes whose overexpression specifically...

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Detalles Bibliográficos
Main Authors: Wuebbles, Ryan D, Long, Steven W, Hanel, Meredith L, Jones, Peter L
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872745/
https://ncbi.nlm.nih.gov/pubmed/20490329
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