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Conserved terminal hairpin sequences of histone mRNA precursors are not involved in duplex formation with the U7 RNA but act as a target site for a distinct processing factor.

The hairpin loop structure and the downstream spacer element of histone mRNA precursors are both needed for efficient 3' end formation in vivo and in vitro. Though generally considered as a single processing signal, these two motifs are involved in different types of interaction with the processing...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Vasserot, A P, Schaufele, F J, Birnstiel, M L
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287265/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2734288/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.12.4345
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