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Short-term memory in gene induction reveals the regulatory principle behind stochastic IL-4 expression

Although cell-to-cell variability has been recognized as an unavoidable consequence of stochasticity in gene expression, it may also serve a functional role for tuning physiological responses within a cell population. In the immune system, remarkably large variability in the expression of cytokine g...

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Detalhes bibliográficos
Main Authors: Mariani, Luca, Schulz, Edda G, Lexberg, Maria H, Helmstetter, Caroline, Radbruch, Andreas, Löhning, Max, Höfer, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872609/
https://ncbi.nlm.nih.gov/pubmed/20393579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.13
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