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Hypoxia-Inducible Factor-1α Stabilizing Genetic Variant and Adverse Outcomes in Acute Kidney Injury

Hypoxia-inducible factor-1α (HIF-1α) is a transcription factor that mediates many cellular responses to tissue hypoxia, a common feature of acute kidney injury (AKI). Here we studied 241 patients with AKI and determined the relationship to adverse outcome of a non-synonymous polymorphism in the codi...

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Detalhes bibliográficos
Main Authors: Kolyada, Alexey Y., Tighiouart, Hocine, Perianayagam, Mary C., Liangos, Orfeas, Madias, Nicolaos E., Jaber, Bertrand L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872511/
https://ncbi.nlm.nih.gov/pubmed/19279559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2009.68
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