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Retrovirus-induced murine motor neuron disease: mapping the determinant of spongiform degeneration within the envelope gene.

The Cas-Br-E murine leukemia virus (MuLV) induces a degenerative myeloencephalopathy leading to hind-limb paralysis when inoculated into newborn mice. To map the viral DNA sequences encoding the determinant of neurological degeneration, we constructed chimeric viruses in vitro with parental genomes...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Paquette, Y, Hanna, Z, Savard, P, Brousseau, R, Robitaille, Y, Jolicoeur, P
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287248/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542954/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3896
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