Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin.

The capacity of Shigella to spread within the cytosol of infected epithelial cells and to infect adjacent cells is critical for the development of infection foci, which lead to mucosal abscesses. Shigella is a nonmotile microorganism that appears to utilize host cell microfilaments to generate intra...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Bernardini, M L, Mounier, J, d'Hauteville, H, Coquis-Rondon, M, Sansonetti, P J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1989
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287242/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3867
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