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Electrophysiology of Reactive Oxygen Production in Signaling Endosomes

Endosome trafficking and function require acidification by the vacuolar ATPase (V-ATPase). Electrogenic proton (H(+)) transport reduces the pH and creates a net positive charge in the endosomal lumen. Concomitant chloride (Cl(−)) influx has been proposed to occur via ClC Cl(−)/H(+) exchangers. This...

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Detalhes bibliográficos
Main Authors: Lamb, Fred S., Moreland, Jessica G., Miller, Francis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872256/
https://ncbi.nlm.nih.gov/pubmed/19207039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2008.2448
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