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A protective monoclonal antibody recognizes a linear epitope in the precursor to the major merozoite antigens of Plasmodium chabaudi adami.

The monoclonal antibody 5C10/66 was shown to afford strong protection in mice against fulminating Plasmodium chabaudi adami infection. This was remarkable, as immunity to this organism is regarded to be mainly T-cell mediated. This antibody identified a 250-kDa molecule in schizonts and an 83-kDa fr...

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Bibliografische gegevens
Hoofdauteurs: Lew, A M, Langford, C J, Anders, R F, Kemp, D J, Saul, A, Fardoulys, C, Geysen, M, Sheppard, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1989
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC287221/
https://ncbi.nlm.nih.gov/pubmed/2471191
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