A protective monoclonal antibody recognizes a linear epitope in the precursor to the major merozoite antigens of Plasmodium chabaudi adami.

The monoclonal antibody 5C10/66 was shown to afford strong protection in mice against fulminating Plasmodium chabaudi adami infection. This was remarkable, as immunity to this organism is regarded to be mainly T-cell mediated. This antibody identified a 250-kDa molecule in schizonts and an 83-kDa fr...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Lew, A M, Langford, C J, Anders, R F, Kemp, D J, Saul, A, Fardoulys, C, Geysen, M, Sheppard, M
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287221/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2471191/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3768
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