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Smoking, gender, and ethnicity predict somatic BRAF mutations in colorectal cancer

Approximately 5 – 15% of all CRCs have an activating BRAF somatic mutation, which may be associated with a distinct risk profile compared to tumors without BRAF mutations. Here, we measured the prevalence and epidemiologic correlates of the BRAF V600E somatic mutation in cases collected as a part of...

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Detalhes bibliográficos
Main Authors: Rozek, Laura S., Herron, Casey M., Greenson, Joel K., Moreno, Victor, Capella, Gabriel, Rennert, Gad, Gruber, Stephen B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872124/
https://ncbi.nlm.nih.gov/pubmed/20200438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-1112
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