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Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast

We show that fluorescence lifetime is a powerful contrast mechanism that can enhance the whole-body imaging of fluorescent proteins (FPs), in the presence of background tissue autofluorescence (AF). The nonexponential AF decay is characterized from time-domain (TD) measurements on multiple nude mice...

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Hlavní autoři: Kumar, Anand T. N., Chung, Euiheon, Raymond, Scott B., van de Water, Jeroen A. J. M., Shah, Khalid, Fukumura, Dai, Jain, Rakesh K., Bacskai, Brian J., Boas, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872111/
https://ncbi.nlm.nih.gov/pubmed/19572001
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