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Commonalities of Genetic Resistance to Spontaneous Autoimmune and Free Radical-Mediated Diabetes

ALR/Lt, a NOD-related mouse strain, was selected for resistance to alloxan free radical mediated diabetes (ALD). Despite extensive genomic identity with NOD (>70%), ALR mice display strong resistance to autoimmune Type 1 diabetes (T1D) due to an unusual elevation in both systemic antioxidant defe...

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Detalhes bibliográficos
Main Authors: Chen, Jing, Lu, Ying, Lee, Chul-Ho, Li, Renhua, Leiter, Edward H., Mathews, Clayton E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872108/
https://ncbi.nlm.nih.gov/pubmed/18718526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.07.020
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