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Commonalities of Genetic Resistance to Spontaneous Autoimmune and Free Radical-Mediated Diabetes
ALR/Lt, a NOD-related mouse strain, was selected for resistance to alloxan free radical mediated diabetes (ALD). Despite extensive genomic identity with NOD (>70%), ALR mice display strong resistance to autoimmune Type 1 diabetes (T1D) due to an unusual elevation in both systemic antioxidant defe...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872108/ https://ncbi.nlm.nih.gov/pubmed/18718526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.07.020 |
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