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Insertional mutation in a transgenic mouse allelic with Purkinje cell degeneration.

Purkinje cell degeneration (pcd) is an autosomal recessive mutation which maps to chromosome 13 in the mouse. The pcd mutation causes loss of cerebellar Purkinje cells, retinal photoreceptor cells, and olfactory bulb mitral cells, as well as abnormalities of spermatogenesis. pcd is among a number of...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Krulewski, T F, Neumann, P E, Gordon, J W
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287209/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726749/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3709
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