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The kinetic basis for age-associated changes in quercetin and genistein glucuronidation by rat liver microsomes.
The dietary bioavailability of the isoflavone genistein is decreased in older rats compared to young adults. Since flavonoids are metabolized extensively by the UDP-glucuronosyltransferases (UGTs), we hypothesized that UGT flavonoid conjugating activity changes with age. The effect of age on flavono...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872046/ https://ncbi.nlm.nih.gov/pubmed/19446449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnutbio.2009.02.006 |
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