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Systemic factors dominate mammal protein evolution
Proteins encoded by highly expressed genes evolve more slowly. This correlation is thought to arise owing to purifying selection against toxicity of misfolded proteins (that should be more crucial for highly expressed genes). It is now widely accepted that this individual (by-gene) effect is a domin...
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| 第一著者: | |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Royal Society
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2871935/ https://ncbi.nlm.nih.gov/pubmed/20053642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2009.1865 |
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