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Direct activation of cGMP-dependent channels of retinal rods by the cGMP phosphodiesterase.

The cationic conductances of purified bovine retinal rod membranes were studied by incorporation of vesicles into planar lipid bilayers. When the membranes were stripped of all peripheral proteins [guanine nucleotide-binding protein (G protein) and cGMP phosphodiesterase (3',5'-cyclic-GMP 5'-nucleot...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bennett, N, Ildefonse, M, Crouzy, S, Chapron, Y, Clerc, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2471190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3634
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