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Use of Bacillus brevis for efficient synthesis and secretion of human epidermal growth factor.

Using previously isolated Bacillus brevis strains that secrete large amounts of proteins but little protease into the medium, we have developed a host-vector system for very efficient synthesis and secretion of heterologous proteins. The multiple promoters and the signal-peptide-coding region of the...

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Detalhes bibliográficos
Main Authors: Yamagata, H, Nakahama, K, Suzuki, Y, Kakinuma, A, Tsukagoshi, N, Udaka, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC287183/
https://ncbi.nlm.nih.gov/pubmed/2786200
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