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Vaccinia DNA topoisomerase I promotes illegitimate recombination in Escherichia coli.

Vaccinia virus encapsidates a Mr 32,000 type IDNA topoisomerase. Although the vaccinia gene encoding the topoisomerase is essential for virus growth, the role of the enzyme in vivo remains unclear. In the present study, the physiologic consequences of vaccinia topoisomerase action have been examined...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Hovedforfatter: Shuman, S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287163/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542933/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.10.3489
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