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Engineering of Single Ig Superfamily Domain of Intercellular Adhesion Molecule 1 (ICAM-1) for Native Fold and Function

The immunoglobulin (Ig) superfamily is one of the largest families in the vertebrate genome, found most frequently in cell surface molecules. Intercellular adhesion molecule-1 (ICAM-1) contains five extracellular Ig superfamily domains (D1-D5) of which the first domain, D1, is the binding site for t...

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Detalhes bibliográficos
Main Authors: Owens, Róisín M., Gu, Xiaoling, Shin, Miran, Springer, Timothy A., Jin, Moonsoo M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871458/
https://ncbi.nlm.nih.gov/pubmed/20304924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.104349
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